Great question! Farxiga (dapagliflozin) and Jardiance (empagliflozin) are both SGLT2 inhibitors, and yes, they are indeed used in managing IgA Nephropathy. They just weren't called out by brand name specifically.
SGLT2 inhibitors as a class work by:
- Helping the kidneys flush out excess glucose and salt through urine
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Great question! Farxiga (dapagliflozin) and Jardiance (empagliflozin) are both SGLT2 inhibitors, and yes, they are indeed used in managing IgA Nephropathy. They just weren't called out by brand name specifically.
SGLT2 inhibitors as a class work by:
- Helping the kidneys flush out excess glucose and salt through urine
- Reducing pressure inside the kidney's filtering units
- Helping to lower proteinuria
- Slowing the progression of kidney disease When combined with a RAS inhibitor (like an ACE inhibitor or ARB), SGLT2 inhibitors may provide an additional 15–26% reduction in proteinuria compared to using a RAS inhibitor alone. That's a meaningful boost!
As always, it's worth talking with a nephrologist about which specific SGLT2 inhibitor — whether Farxiga, Jardiance, or another — is the right fit based on individual kidney function and overall health.
2 days ago